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Chemical peels
Alpha-hydroxy, salicylic and trichloroacetic acids, phenol
How it works
An acid on the skin, reaching deeper the stronger it is
- Superficial · alpha-hydroxy acids, to the epidermis3 – 30 %
- Medium · trichloroacetic acid, to the papillary dermis35 %
- Deep · trichloroacetic acid, or phenol, to the reticular dermisabove 40 %
Each front is its own agent at its own strength, not one scale. Trichloroacetic acid and phenol are not permitted in cosmetics in Canada.
- Superficial · alpha-hydroxy acids, to the epidermis3 – 30 %
- Medium · trichloroacetic acid, to the papillary dermis35 %
- Deep · trichloroacetic acid, or phenol, to the reticular dermisabove 40 %
Each front is its own agent at its own strength, not one scale. Trichloroacetic acid and phenol are not permitted in cosmetics in Canada.
What it costs
Treating the face costs $175 – $330 a peel on clinic pages
Tap to add or remove an area. Quoted combinations apply where listed.
| Area | One peel |
|---|---|
| glycolic, salicylic or Jessner’s solution | $175 – $330a peel |
| on its own | $94a peel |
Results & duration
Results differ for acne and sun spots
Doctor-rated improvement, acne
Excellent or good at ten weeks
92%Glycolic acid side · of 25 people
Moderate acne: 40% glycolic acid on one half of the face and placebo on the other, five peels 2 weeks apart, at Wakayama Medical University. The count is the review’s; the paper is not open.
Chen 2018, PMID 29705755, reporting Kaminaka 2014, PMID 24447110
Sun spots, success as each trial counted it
Trichloroacetic acid peel
12 – 46%
The share of people reaching their trial’s mark for success, across the trichloroacetic acid trials a systematic review of solar lentigines found, each trial’s mark its own; intense pulsed light 74.6 to 90% in the same review.
How long does a chemical peel last?
Not measured past 10 weeks in the acne trial, which ended 2 weeks after the fifth peel. Clinic pages say 1 to 2 months for a light peel and up to 6 months for a medium one, with a maintenance peel every month, every 4 months, or once a season, each its own page’s word. The photoaging trials followed people 3 to 12 months after the last peel and report improvement holding at those visits, not when it ended.
Chen 2018, PMID 29705755 · Sitohang 2021, PMID 34504524 · clinic pages
Recovery & risks
Recovery depends on the peel’s depth
Clinic pages, the trichloroacetic acid review and Kaminaka 2014 · 25 people
- Dryness, mild28%
- Scaling16%
- Acne flare12%
- Downtime
- Flaking or shedding for 1 to 7 days on the clinic pages, none for the lightest peel on one page; 14 days for a deep peel on one.
- Right after
- Burning and stinging as the acid goes on, the trichloroacetic acid review says. In the acne trials, redness lasting a few minutes at most after glycolic acid; burning in more than 85% with salicylic or pyruvic acid.
- Weeks later
- Redness persisting up to one month after a 35% peel in one trial. Hyperpigmentation, hypopigmentation and scarring are the long-term side effects, the trichloroacetic acid review says; scarring only on the peeled side in the one trial reporting it.
- Next peel
- 2 weeks apart, five times, in the acne trial; 2 to 8 weeks on the clinic pages, most saying 2 to 4, for a series of 3 to 6.
Side effects the review names
Hyperpigmentation, hypopigmentation, scarring: named by the review, which gives no rate.
Darker or lighter patches
Scarring
Long-term side effects of trichloroacetic acid peeling, as the systematic review names them · Illustrations are schematic.
Frequently asked questions
Sources
- Health Canada · Cosmetic Ingredient Hotlist (2025-08-13)
- Fischer et al. · Chemical peels in aesthetic dermatology, JEADV (2010)
- Sitohang 2021, PMID 34504524 · Trichloroacetic acid peeling for treating photoaging, a systematic review
- Bommareddy 2026, PMID 41147724 · Histologic changes after chemical peeling, Dermatologic Surgery
- Chen 2018, PMID 29705755 · Chemical peels for acne vulgaris, a systematic review of randomised trials, BMJ Open, reporting Kaminaka 2014, PMID 24447110
- Mardani 2025, PMID 40145274 · Treatment of solar lentigines, a systematic review of clinical trials, J Cosmet Dermatol
- Excise Tax Act · s. 165, Sch. V Pt. II, Sch. VIII
- Health Canada · Classification of Products at the Cosmetic-Drug Interface
- Ontario e-Laws · Regulated Health Professions Act, 1991, ss. 27 and 30, and O. Reg. 107/96, Controlled Acts